A-Projects: Disease Mechanisms: DFG Collaborative Research Centre 1470 - Charité – Universitätsmedizin Berlin

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Charité – Universitätsmedizin Berlin

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A - Projekte: Disease mechanisms

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Subprojects in the area A investigate the mechanisms underlying the development of HFpEF.

Subprojects of the area A

A01 - Heinzel/Paolo Ventricular compartmentalization and functional reserve in cardiomyocytes in HFpEF

A05 - Dechend/Forslund Role of sex hormones on microbiome, immunity, and coronary microvascular dysfunction and rarefication in experimental HFpEF

A09 - Kintscher/Sigrist Lipid-mediated mitochondrial dysfunction in HFpEF during obesity

A02 - Schiattarella Lipid-based control of the unfolded protein response in HFpEF

A06 - Sawamiphak/Müller Immune regulation of vascular rarefaction and diastolic myocardial remodeling

A10 - Wilck Connecting the gut microbiota to the cardiorenal axis in HFpEF

A03 - Gerhardt/Landmesser Linking metabolism, mechanotransduction and endothelial dysfunction in HFpEF

A07 - van Linthout Sterile inflammation and innate immunity in HFpEF

A04 - Kübler/Grune Cardio-pulmonary interaction in HFpEF

A08 - Beling/Berndt Metabolic reprogramming steered by ISGylation in HFpEF